The development of systemic lupus erythematosus following interferon‐α therapy for hepatitis C infection
Identifieur interne : 001C50 ( Main/Exploration ); précédent : 001C49; suivant : 001C51The development of systemic lupus erythematosus following interferon‐α therapy for hepatitis C infection
Auteurs : S-Abdul Wahid Fadilah ; Kong-Chiew-Tong Norella ; Mohd-Said Shahril ; Raja-Sabudin Azma [Malaisie] ; Chooi-Fun Leong [Malaisie] ; Soon-Keng CheongSource :
- APLAR Journal of Rheumatology [ 0219-0494 ] ; 2006-09.
English descriptors
- Teeft :
- Aplar, Aplar journal, Autoantibody, Autoimmune, Autoimmune disease, Autoimmune phenomena, Case report, Clin rheumatol, Clinical manifestations, Dendritic, Dendritic cells, Discoid rash, Discontinuation, Erythematosus, Family history, Interferon, Interferon therapy, Kuala lumpur, Laboratory markers, Lupus, Malaysia, Numerous spherocytes, Peripheral blood, Platelet, Platelet count, Rheumatology, Serum transaminases, Systemic, Systemic lupus erythematosus, Universiti kebangsaan malaysia.
Abstract
Interferon‐alpha (IFN‐α) therapy has been associated with de novo development of systemic lupus erythematosus (SLE), and discontinuation of IFN‐α resulted in disease resolution in most patients. Recurrence of SLE in the absence of concomitant IFN‐α therapy has not been reported. We present here a woman who developed overt clinical manifestations of SLE one year after withdrawal of IFN‐α therapy for hepatitis C virus (HCV) infection. This report highlights the importance of long‐term follow‐up for the belated development of SLE in patients who have experienced IFN‐α induced autoimmune phenomena.
Url:
DOI: 10.1111/j.1479-8077.2006.00216.x
Affiliations:
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type="abstract" xml:lang="en">Interferon‐alpha (IFN‐α) therapy has been associated with de novo development of systemic lupus erythematosus (SLE), and discontinuation of IFN‐α resulted in disease resolution in most patients. Recurrence of SLE in the absence of concomitant IFN‐α therapy has not been reported. We present here a woman who developed overt clinical manifestations of SLE one year after withdrawal of IFN‐α therapy for hepatitis C virus (HCV) infection. This report highlights the importance of long‐term follow‐up for the belated development of SLE in patients who have experienced IFN‐α induced autoimmune phenomena.</div></front></TEI><affiliations><list><country><li>Malaisie</li></country></list><tree><noCountry><name sortKey="Cheong, Soon Eng" sort="Cheong, Soon Eng" uniqKey="Cheong S" first="Soon-Keng" last="Cheong">Soon-Keng Cheong</name><name sortKey="Norella, Kong Hiew Ong" sort="Norella, Kong Hiew Ong" uniqKey="Norella K" first="Kong-Chiew-Tong" last="Norella">Kong-Chiew-Tong Norella</name><name sortKey="Shahril, Mohd Aid" sort="Shahril, Mohd Aid" uniqKey="Shahril M" first="Mohd-Said" last="Shahril">Mohd-Said Shahril</name><name sortKey="Wahid Fadilah, S Bdul" sort="Wahid Fadilah, S Bdul" uniqKey="Wahid Fadilah S" first="S-Abdul" last="Wahid Fadilah">S-Abdul Wahid Fadilah</name></noCountry><country name="Malaisie"><noRegion><name sortKey="Azma, Raja Abudin" sort="Azma, Raja Abudin" uniqKey="Azma R" first="Raja-Sabudin" last="Azma">Raja-Sabudin Azma</name></noRegion><name sortKey="Leong, Chooi Un" sort="Leong, Chooi Un" uniqKey="Leong C" first="Chooi-Fun" last="Leong">Chooi-Fun Leong</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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